pentobarbital will decrease the level or result of nitrendipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
pentobarbital will decrease the extent or outcome of atazanavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.
pentobarbital will lower the extent or impact of fruquintinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavoidable, continue to administer fruquintinib at advisable dosage.
Contraindicated (1)pentobarbital will reduce the extent or effect of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or outcome of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Strong CYP3A4 inducers may perhaps lower partiaprevir and ritonavir stages, and so decreased efficacy of Viekira Pak
pentobarbital will lessen the extent or outcome of sufentanil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
pentobarbital will minimize the extent or influence of ambrisentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
pentobarbital will minimize the level or outcome of terbinafine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Observe Closely (one)pentobarbital will decrease the extent or effect of cannabidiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or effect of tramadol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Lowered AUC of tramadol along with the Energetic metabolite (O-desmethyltramadol) when coadministered with solid CYP3A4 and CYP2B6 inducers
Observe Carefully (one)pentobarbital will lower the level or influence of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify get more info Therapy/Watch Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on to some decrease in fentanyl plasma concentrations, lack of efficacy or, perhaps, progress of the withdrawal syndrome in a affected person that has designed Bodily dependence to fentanyl. Just after halting a CYP3A4 inducer, as the effects from the inducer decline, the fentanyl plasma concentration will boost which could boost or prolong both the therapeutic and adverse effects.
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pentobarbital will lower the level or outcome of ripretinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the level or effect of conjugated estrogens, vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.